Table 1.
Univariate and multivariate analysis of clinical, pathological and molecular variables for disease-specific survival in 214 HCC
| |
Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| Variables | HR | 95% CI | P | HR | 95% CI | P |
| Cirrhosis |
1.45 |
0.90-2.31 |
0.119 |
- |
- |
- |
| Multiple tumors |
1.952 |
1.09-3.49 |
0.024 |
3.53 |
1.83-6.81 |
0.000167 |
| HCC > 5 cm |
1.705 |
1.04-2.80 |
0.035 |
1.88 |
1.01-3.47 |
0.044943 |
| AFP > 20 ng/ml |
2.04 |
1.25-3.32 |
0.0043 |
1.58 |
0.90-2.76 |
0.107818 |
| Microvascular invasion |
2.98 |
1.86-4.78 |
5.83e-06 |
1.98 |
1.09-3.60 |
0.024328 |
| Tumor portal thrombosis |
3.59 |
2.14-6.01 |
1.21e-06 |
1.92 |
1.01-3.66 |
0.045599 |
| Differentiation: Edmonson III/IV |
1.60 |
1.01-2.52 |
0.0436 |
0.88 |
0.50-1.54 |
0.653579 |
| PI4KA high level | 2.22 | 1.39-3.54 | 0.000823 | 2.36 | 1.27-4.36 | 0.006415 |
Bold values represent P values considered to be statistically significant (<0.05).
HR: hazard ratio; CI: confidence interval.