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. 2013 Dec;34(12):2890.e1–2890.e5. doi: 10.1016/j.neurobiolaging.2013.06.005

Fig. 1.

Fig. 1

Pedigree of the family where the compound heterozygous mutation p.[(Y38C)];[(D86V)] in TREM2 was found. The arrowhead indicates the proband. Black filled symbols represent affected subjects with dementia. White symbols represent unaffected family members. The TREM2 variants found are represented below each individual showing segregation of the compound heterozygous mutation with the disease.