Figure 6.

Characteristics of REM in control and epileptic animals. Typical transitions out of REM are shown for preseizure (PS; top) and interseizure (IS; middle) REM bouts in an epileptic animal and for a control animal (bottom). Preseizure REM bouts end in seizure and interseizure, and control REM bouts end in either NREM or Wake. Signals reflect LFPs recorded from the left dorsal hippocampus, bandpass filtered between 0.5 and 35 Hz and aligned to the end of the REM bout marked by the vertical line. Interictal epileptic discharges can be seen in both preseizure and interseizure REM bouts but not in control animals.