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. 2014 Jan 22;34(4):1358–1369. doi: 10.1523/JNEUROSCI.4592-13.2014

Figure 2.

Figure 2.

Effect of D1R and D2R blockade in the NAc shell and core on expression of specific Pavlovian-instrumental transfer. A, All rats received Pavlovian and instrumental training followed by two consecutive PIT tests. One group performed these two tests under NAc-S infusion of either VEH or a high dose of SCH, while another group was infused with either vehicle or a high dose of RAC. Following instrumental retraining, rats were again submitted to two consecutive PIT tests that were identical to the previous ones except that low doses of SCH and RAC were infused into the NAc-S. B, Rats infused with vehicle exhibited specific PIT. Although both doses of SCH impaired specific PIT, only the low dose did so without affecting baseline performance. C, Rats displayed specific PIT whether they were infused in the NAc-S with vehicle or the low and high dose of RAC. D, The performance during the tests revealed that animals exhibited specific PIT whether they had been infused into the NAc-C with VEH, SCH, or RAC. E, Placements of the injection cannula tips in the NAc-S (left) and NAc-C (right) for rats infused with SCH (blue) and RAC (red). Distances on the atlas templates are indicated in millimeters relative to bregma.