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. 2013 Dec 30;13:616. doi: 10.1186/1471-2407-13-616

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Copyright © 2013 Lenhard et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Glycodelin as well as its immunosuppressive glyco-variant Glycodelin A protein was analysed and quantified in endometrial cancer tissue. Quantification of Glycodelin (Gd; A, C, E) and its immunosuppressive glyco-variant Glycodelin A (GdA; B, D, F) by immunohistochemistry is shown. Gd/GdA was visualized in endometrial carcinoma tissue of different histological subtypes (A, B), FIGO stages (C, D) or tumour grades (E, F). Gd and GdA were detected by immuno-histochemistry and quantified employing an immunoreactive score (IRS) ranging from 0 (lowest) to 12 (highest). Significant differences (p < 0.05) as determined by Mann–Whitney Test are indicated by #.