Table 5.
Exposure | Fixed increment | Cohorts | Participants | Pooled hazard ratios (95% CI) | ||
---|---|---|---|---|---|---|
Model 1* | Model 2† | Model 3‡ | ||||
PM10 (µg/m3) | 10 | 11 | 100 166 | 1.15 (1.04 to 1.28) | 1.12 (1.01 to 1.24) | 1.12 (1.01 to 1.25) |
Coarse PM (µg/m3) | 5 | 11 | 100 166 | 1.08 (1.00 to 1.17) | 1.06 (0.98 to 1.14) | 1.06 (0.98 to 1.15) |
PM2.5 (µg/m3) | 5 | 11 | 100 166 | 1.22 (1.04 to 1.44) | 1.15 (1.00 to 1.32) | 1.13 (0.98 to 1.30) |
Absorbance PM2.5 (10−5/m) | 1 | 11 | 100 166 | 1.18 (1.05 to 1.32) | 1.10 (0.98 to 1.24) | 1.10 (0.98 to 1.24) |
NO2 (µg/m3) | 10 | 11 | 100 166 | 1.04 (0.96 to 1.12) | 1.03 (0.96 to 1.11) | 1.03 (0.97 to 1.08) |
NOx (µg/m3) | 20 | 11 | 100 166 | 1.03 (1.00 to 1.07) | 1.01 (0.98 to 1.05) | 1.01 (0.98 to 1.05) |
Traffic intensity on nearest road adjusted for background NO2 (vehicles/day)§ | 5000 | 10 | 95 733 | 1.01 (0.98 to 1.04) | 1.01 (0.98 to 1.04) | 1.01 (0.98 to 1.04) |
Traffic load on major roads in 100 m buffer adjusted for background NO2 (vehicles×m/day) | 4 000 000 | 11 | 100 166 | 1.02 (0.96 to 1.08) | 1.00 (0.95 to 1.06) | 1.00 (0.95 to 1.06) |
*Adjusted for age (time variable), year of enrolment and sex
†As for model 1 plus adjusted for marital status, education, occupation, smoking status, smoking duration, and smoking intensity.
‡As for model 2 plus adjusted for socioeconomic area level variables.
§All cohorts except HNR study.24