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Glucose Supplementation Blocks Metformin-Induced Lifespan Extension, Related to Figure 7
(A) Metformin does not extend C. elegans lifespan in the presence of 1% d-glucose.
(B) Glucose supplementation alone slightly enhances bacterial growth.
(C and D) 1% d-glucose reverses inhibition of bacterial growth by 50 mM metformin.
See Table S7 for statistics. Error bars, SEM. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.
