Figure 5.

Natural killer (NK) T cells retain functional capacity after autologous stem cell transplantation (ASCT). Peripheral blood mononuclear cells (PBMCs) were stimulated ex vivo with phorbol myristate acetate (PMA)/ionomycin for 4 h. (a) Representative fluorescence activated cell sorter (FACS) plots from previously untreated patients are shown. (b) The percentage of NKT cells capable of interferon (IFN)-γ, tumour necrosis factor (TNF) and interleukin (IL)-4 production was assessed for four patients with sufficient NKT cells for cytokine analysis.