Fig. 14.
Co-crystal structure of T220C p53 mutant and fragment 10, this compound was discovered via fragment screening (PDB ID: 2XOW). Key interacting amino acids of p53 binding shown in yellow sticks.
Co-crystal structure of T220C p53 mutant and fragment 10, this compound was discovered via fragment screening (PDB ID: 2XOW). Key interacting amino acids of p53 binding shown in yellow sticks.