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. Author manuscript; available in PMC: 2014 Jan 22.
Published in final edited form as: Medchemcomm. 2011 Mar 9;2:246–260. doi: 10.1039/C0MD00248H

Fig. 15.

Fig. 15

Co-crystal structure of T220C p53 mutant (green cartoon) and fragment 11 (blue sticks). This compound was discovered via fragment screening (PDB ID: 2XOV). Key interacting amino acids of p53 binding shown in yellow sticks.