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. Author manuscript; available in PMC: 2014 Jan 22.
Published in final edited form as: Medchemcomm. 2011 Mar 9;2:246–260. doi: 10.1039/C0MD00248H

Fig. 6.

Fig. 6

Co-crystal structure of Johnson & Johnson’s benzodiazepine small molecule 2 (green sticks, PDB ID: 1T4E) and MDM2 (grey surface) superimposed on the key amino acid side chain residues of the p53/ MDM2 structure (yellow sticks, PDB ID: 1YCR).