Table 1.
Demographic, anthropometric, and clinical characteristics of subjects with low hepatic fat content compared to subjects with high hepatic fat content (%), adjusted for age, gender, race/ethnicity
| Low hepatic fat content <5.5% (n = 13) | High hepatic fat content >5.5% (n = 13) | P value | P value adjusted | |
|---|---|---|---|---|
| Age (years) | 16.2 (14.4, 18.1) | 14.8 (13.2, 16.5) | 0.352 | |
| Gender-no. (%)a | 0.430 | |||
| Male (n = 14) | 6 (46%) | 8 (61.5%) | ||
| Female (n = 12) | 7 (54%) | 5 (38.5%) | ||
| Race/ethnicity-no. (%)a | 0.625 | |||
| White (n = 8) | 4 (30.8%) | 4 (30.8%) | ||
| African American (n = 9) | 5 (38.5%) | 4 (30.8%) | ||
| Hispanic (n = 9) | 4 (30.8%) | 5 (38.5%) | ||
| Weight (kg) | 106.8 (93.3, 120.2) | 108.9 (93.1, 124.7) | 0.739 | 0.669 |
| BMI (kg/m2) | 36.8 (32.6, 41.0) | 39.6 (35.3, 43.8) | 0.369 | 0.280 |
| BMI z-score | 2.2 (1.9, 2.5) | 2.6 (2.4, 2.8) | 0.050 | 0.196 |
| Waist (cm) | 103.2 (89.3, 117.1) | 115.0 (105.8, 124.2) | 0.184 | 0.300 |
| DEXA | ||||
| %Fat | 37.2 (31.7, 42.6) | 40.0 (36.7, 43.2) | 0.694 | 0.115 |
| Tissue lipid content | ||||
| Liver | ||||
| Hepatic fat fraction (HFF%) | 1.5 (–0.4, 3.3) | 18.4 (11.4, 25.5) | 0.000 | 0.000 |
| Abdominal Region | ||||
| VAT (cm2) | 72.5 (49.9, 95.2) | 86.5 (67.5, 105.6) | 0.228 | 0.143b |
| SAT (cm2) | 616.0 (471.3, 760.7) | 599.5 (480.3, 718.6) | 0.898 | 0.911b |
| VAT/VAT + SAT | 0.107 (0.084, 0.129) | 0.131 (0.099, 0.164) | 0.228 | 0.043b |
| DeepSubQ (cm2) | 220.9 (161.1, 280.8) | 222.9 (169.0, 276.7) | 0.870 | 0.917b |
| SupSubQ (cm2) | 142.0 (111.3, 172.6) | 145.6 (110.0, 181.1) | 0.786 | 0.758b |
| Deep/Deep+SupSubQ | 0.601 (0.550, 0.652) | 0.599 (0.544, 0.653) | 0.957 | 0.583b |
Data are presented as means (95% CI). P value in bold indicate significance (P < 0.05).
DeepSubQ, deep subcutaneous adipose tissue; SAT, subcutaneous adipose tissue; SupSubQ, superficial subcutaneous adipose tissue; VAT, visceral adipose tissue.
a
Fishers exact test.
b
P value for log transformed data.