Table 1.
Clinical Characteristics of the Patients
Subject 1 | Subject 2 | Subject 3 | Subject 4 | Subject 5 | |
---|---|---|---|---|---|
Primary Pathology | Well-differentiated NET, ileal primary | Well-differentiated NET, ileal primary | Well-differentiated NET, pancreatic gastrinoma | Well-differentiated NET, unknown primary | Well-differentiated NET; ileal primary |
Symptoms & Biomarkers | Carcinoid Syndrome, elevated serotonin, CgA and pancreastatin | Carcinoid Syndrome, elevated serotonin, CgA and pancreastatin | No symptoms, elevated gastrin | Carcinoid Syndrome, elevated serotonin, CgA and pancreastatin | Carcinoid Syndrome, elevated serotonin, CgA and pancreastatin |
Treatment | Octreotide LAR | Octreotide LAR and octreotide SQ; Previous course of everolimus | Octreotide LAR; Previous hepatic chemo- embolization | Octreotide SQ; Previous PRRNT | Octreotide LAR and octreotide SQ |
CgA: Chromogranin A SQ: subcutaneous LAR: long-acting release PRRNT: peptide receptor radionuclide therapy