Table 2.
Crude and adjusted odds ratios of developing offspring macrosomia
|
Macrosomia (birthweight >4000 g) |
||||
---|---|---|---|---|---|
|
(%) |
Crude OR |
p-value |
Adjusted OR |
p-value |
(95% CI) | (95% CI) | ||||
Pre-gestational BMI* |
|
|
|
|
|
18.5-24.9 |
(6.9) |
1 |
|
1 |
|
<18.5 |
(2.8) |
0.4 (0.3 - 0.6) |
<0.001 |
0.5 (0.3-0.7) |
<0.001 |
25-29.9 |
(10.4) |
1.6 (1.3 - 1.8) |
<0.001 |
1.1 (0.9-1.3) |
0.319 |
≥30 |
(15.7) |
2.5 (2.0 - 3.1) |
<0.001 |
1.7 (1.4-2.2) |
<0.001 |
Gestational weight gain |
|
|
|
|
|
Recommended by IOM |
(6.5) |
1 |
|
1 |
|
< Recommended by IOM |
(4.1) |
0.6 (0.5 - 0.7) |
<0.001 |
0.6 (0.5-0.8) |
<0.001 |
> Recommended by IOM |
(12.6) |
2.1 (1.8 - 2.4) |
<0.001 |
1.9 (1.6-2.2) |
<0.001 |
Parity |
|
|
|
|
|
Primiparous |
(5.8) |
1 |
|
1 |
|
Multiparous |
(9.6) |
1.7 (1.5 - 1.9) |
<0.001 |
2.0 (1.7-2.3) |
<0.001 |
Maternal Diabetes |
|
|
|
|
|
No |
(7.4) |
1 |
|
1 |
|
Gestational diabetes |
(14.2) |
2.1 (1.5 - 2.8) |
<0.001 |
2.1 (1.5-3.0) |
<0.001 |
Pre-gestational diabetes |
(16.7) |
2.5 (1.0 - 6.1) |
0.032 |
3.0 (1.2-7.6) |
0.023 |
Maternal height (cm) |
|
|
|
|
|
≤165 |
(5.6) |
1 |
|
1 |
|
>165 |
(9.7) |
1.8 (1.6 - 2.1) |
<0.001 |
1. 9 (1.6-2.2) |
<0.001 |
Gestational age (weeks) |
|
|
|
|
|
37-40 |
(5.4) |
1 |
|
1 |
|
>40 |
(16.9) |
3.5 (3.1 - 4.0) |
<0.001 |
3. 7 (3.2-4.2) |
<0.001 |
Neonate sex |
|
|
|
|
|
Female |
(5.0) |
1 |
|
1 |
|
Male | (10.1) | 2.1 (1.9 - 2.4) | <0.001 | 2.2 (2.0-2.6) | <0.001 |
*Test for Trend: p <0.001.