Table VII.
Apa1 and breast cancer.
Population studied | Study type | Polymorphism | Cases/controls | Results | Refs. |
---|---|---|---|---|---|
Australian | CCS | Apa1, Fok1, Taq1 | 135/410 | The Aa and aa genotypes are associated with breast cancer risk | (72) |
Taiwanese | CCS | Apa1, Bsm1, Taq1 | 80/169 | The AA genotype is associated with breast cancer risk | (81) |
Finnish | CCS | Apa1, Taq1, Apa1 | 483/482 | Variant ‘a’ genotype is linked to lower risk | (86) |
Caucasian | NCCS | Apa1, Bsm1, Fok1, Taq1, poly(A) | 500/500 | No association | (71) |
Indian | CCS | Apa1, Taq1, poly(A) | 160/140 | No association | (85) |
CCS, case-control study; PCCS, population-based case-control study; NCCS, nested case-control study.