Table 2.
Correlation of PRDM1 and miR-223 expression with clinical factors and prognostic value
| |
|
|
PRDM1 expression |
|
|
|
miR-223 expression |
|
||
|---|---|---|---|---|---|---|---|---|---|---|
| n | Percent | Negative | Positive | P | n | Percent | Negative | Positive | P | |
|
Patients |
61 |
|
|
|
|
31 |
|
|
|
|
| male |
34 |
55.74 |
26 |
8 |
0.829 |
19 |
61.29 |
5 |
14 |
0.704 |
| female |
27 |
44.26 |
20 |
7 |
|
12 |
38.71 |
4 |
8 |
|
|
Age (year) |
61 |
|
|
|
|
31 |
|
|
|
|
| <40 |
29 |
47.54 |
21 |
8 |
0.463 |
13 |
41.94 |
4 |
9 |
NA※ |
| 40-60 |
20 |
32.79 |
17 |
3 |
|
11 |
35.48 |
2 |
9 |
|
| >60 |
12 |
19.67 |
8 |
4 |
|
7 |
22.58 |
2 |
5 |
|
|
Stage
∆
|
46 |
|
|
|
|
26 |
|
|
|
|
| І/ІІ |
18 |
39.13 |
9 |
9 |
0.009 |
9 |
34.62 |
3 |
6 |
0.661 |
| III/IV |
28 |
60.87 |
24 |
4 |
|
17 |
65.38 |
4 |
13 |
|
|
Outcome |
35 |
|
|
|
|
21 |
|
|
|
|
| alive |
12 |
34.29 |
6 |
6 |
0.038 |
8 |
38.10 |
3 |
5 |
0.325 |
| dead |
23 |
65.71 |
20 |
3 |
|
13 |
61.90 |
2 |
11 |
|
|
5-year OS |
35 |
|
|
|
|
21 |
|
|
|
|
| Mean ± SD |
|
|
39.49 ± 9.62 |
64.02 ± 11.48 |
0.045 |
|
|
53.40 ± 18.41 |
45.70 ± 10.05 |
0.504 |
|
OS |
35 |
|
|
|
|
21 |
|
|
|
|
| Mean ± SD |
|
|
44.72 ± 10.41 |
64.02 ± 11.48 |
0.084 |
|
|
53.40 ± 18.41 |
52.84 ± 10.70 |
0.784 |
|
FFS |
35 |
|
|
|
|
21 |
|
|
|
|
| Mean ± SD | 26.50 ± 5.60 | 57.41 ± 11.60 | 0.042 | 43.20 ± 16.89 | 38.99 ± 7.84 | 0.691 | ||||
※NA, not analyzed, because of limited sample size.
△Ann Arbor Stage.