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. Author manuscript; available in PMC: 2014 Jan 22.
Published in final edited form as: Proc SPIE Int Soc Opt Eng. 2010 Aug 27;7762:77621T. doi: 10.1117/12.862519

Figure 1.

Figure 1

(A–D) Schematic showing the optical trapping of a single nanocapsule (A), positioning of the nanocapsule next to a biological cell (B), application of a single UV laser pulse to photolyze the capsule (C), which then causes the release of the contents of the nanocapsule onto the cell (D). (E, F) Experimental images showing a fluo3-loaded CHO-M1 cell before (E) and after (F) release of carbachol from the nanocapsule (upper right circle) onto the cell. Calcium response is clearly visible in the CHO-M1 cell in response to activation by carbachol from the nanocapsule1,2.