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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2013 Apr 10;19(7):1033–1039. doi: 10.1016/j.bbmt.2013.04.005

Table 5.

Incidences of sinusoidal obstruction syndrome and liver disease of unknown etiology among patients conditioned with TBU/CY vs. CY/TBU.

CY/TBU (n=51) TBU/CY (n=271)

Myelofibrosis 20 33
 No liver disease 17 (85%) 19 (58%)
 LDUE 3 (15%) 4 (12%)
 SOS 0(0%) 10 (30%)
  Mild 0 2
  Moderate 0 6
  Severe 0 2

AML/MDS 31 238
 No liver disease 26 (84%) 203 (85%)
 LDUE 3 (10%) 13 (5%)
 SOS 2 (6%) 22 (9%)
  Mild 0 3
  Moderate 2 10
  Severe 0 9

Abbreviations: CY, cyclophosphamide; TBU, targeted busulfan; LDUE, liver disease of unknown etiology; SOS, sinusoidal obstruction syndrome; AML, acute myeloid leukemia; MDS, myelodysplastic syndrome.