Table 5.
CY/TBU (n=51) | TBU/CY (n=271) | |
---|---|---|
| ||
Myelofibrosis | 20 | 33 |
No liver disease | 17 (85%) | 19 (58%) |
LDUE | 3 (15%) | 4 (12%) |
SOS | 0(0%) | 10 (30%) |
Mild | 0 | 2 |
Moderate | 0 | 6 |
Severe | 0 | 2 |
| ||
AML/MDS | 31 | 238 |
No liver disease | 26 (84%) | 203 (85%) |
LDUE | 3 (10%) | 13 (5%) |
SOS | 2 (6%) | 22 (9%) |
Mild | 0 | 3 |
Moderate | 2 | 10 |
Severe | 0 | 9 |
Abbreviations: CY, cyclophosphamide; TBU, targeted busulfan; LDUE, liver disease of unknown etiology; SOS, sinusoidal obstruction syndrome; AML, acute myeloid leukemia; MDS, myelodysplastic syndrome.