Fig. 9.

Different vibrational spectra of water in bulk conditions (left), and in droplets of 2.5 (middle) and 7.5 nanometers (right) in size. Many properties of water including diffusivity, viscosity, dielectric permittivity, polarity and acidification gradients have been shown to change depending on the size of aqueous droplets, implying that different environmental contexts trigger different physicochemical behavior of water confined to nanosized spaces, such as in biological environments. Reprinted with permission from Ref. Crupi et al. 2007