(a) CS2 parasites were selected on ICAM-1 and then cloned, and the number of infected erythrocytes of each clone that bound per square millimeter to immobilised CSA, CD36, and ICAM-1 was determined. (b) The numbers of erythrocytes infected with CS2 clones and E8B parasites that bound per square millimeter to immobilised CSA, CD36, and ICAM-1 at different time points following selection on ICAM-1. Means of three replicates for each of two assays conducted on separate days; error bars are standard error of the mean.