Table 4. Lopinavir and ritonavir pharmacokinetic parameters.

	Lopinavir			Ritonavir
	RBT OD	RBT TPW	All patients	RBT OD	RBT TPW	All patients
Cmax – ng/ml	15439 (7540–34490)	18154 (7803–39550)	16 065 (7540–39550)	777 (332–1587)	816 (405–2484)	815 (32–2484)
C0 – ng/mL	9155 (399–27567)	8014 (50–31171)	8739 (<50– 31171)	314 (25– 569)	257 (25–680)	303 (25–680)

Data are presented as medians with the range in parenthesis

RBT  =  rifabutin; OD  =  once daily; TPW  =  three times per week; Cmax  =  peak concentration; C0  =  trough concentration. All patients: data pooled whatever the RBT dosing 150 mg OD or 150 mg TPW.