Table 2. Multivariate survival analysis in patients with lung adenocarcinoma.

Dataset	Clinical variables*	Multivariate analysis (P<0.05)	Final model†
CANDF (N = 73)	CCP score, stage, grade, chemotherapy, smoking history, age, gender	CCP score, chemotherapy, age	CCP score, chemotherapy, age
MKS (N = 98)	CCP score, stage, grade, radiotherapy treatment, chemotherapy, smoking history, age, gender	Grade	Grade, chemotherapy
Takeuchi (N = 90)	CCP score, stage, grade, EGFR status, KRAS status, p53 status, smoking history, age, gender	CCP score	CCP score, stage
Tomida (N = 116)	CCP score, stage, EGFR status, KRAS status, p53 status, smoking history, age, gender	CCP score	CCP score, stage

^*Variables include the following (see Table S8 in File S4 for complete multivariate analysis):

Stage: I vs. II (CANDF), I vs. II vs. III (MKS, Takeuchi, Tomida).

Grade: Well vs. moderately vs. poorly differentiated.

Smoking history: current/former vs. never-smoker.

EGFR, KRAS, and p53 status: mutant vs. wild-type.

^†Final model is constructed from forward step-wise regression of significant variables (P<0.05).