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. 2014 Jan;1842(1):1–6. doi: 10.1016/j.bbadis.2013.10.007

Fig. 2.

Fig. 2

(A) Missense mutations in huCOQ6-isoa and the corresponding residues in yCoq6. (B) Schematic representation of the huCOQ6-isoa constructs carrying the W447X and Q461fs478X mutations and their counterpart in yCOQ6. Growth assay (C) and CoQ6 levels (D) in mitochondria from Δcoq6 cells expressing different yCoq6 mutants under the control of the endogenous yeast promoter.