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. 2004 Mar 19;6:23–34. doi: 10.1251/bpo70

Fig. 5. Sample heterogeneity due to different oligomeric states.

Fig. 5

Image of negatively stained T7 helicase/primase in the presence of dTDP. While the particles appear rather homogeneous in the micrograph, image classification revealed the protein formed six- (inset 1) as well as seven-membered rings. The scale bar corresponds to 50 nm and the inset panels have a side length of 30 nm.