Figure 1.

The connectivity matrices for two conformations of protein 2mcm generated by using Eq. 2 with k = 2 and ${\sigma }_{\mathit{i}\mathit{j}}=6$. Diagonal elements have been excluded to emphasize non diagonal interactions. (a) The connectivity matrix of the native structure of 2mcm shown in Fig. 3a indicates much nonlocal interactions. (b) The connectivity matrix of a completely unfolded conformation shown in Fig. 3g demonstrates little nonlocal interactions.