Figure 3.

The spectacular correlation between folded residues and controlled chaos in the dynamics of macromomycin. Forty partially folded or totally unfolded conformations are generated by pulling the folded structure (PBD ID: 2mcm). (a) The ${\mathrm{C}}_{\alpha }$ atoms of the native folded structure. (b) The synchronous dynamics of a 3D ILDM for the native folded structure. (c) The ${\mathrm{C}}_{\alpha }$ atoms of partially ordered Conformation 14. (d) The partial ordered chaotic dynamics of Conformation 14. The first 30 residues are unfolded, which leads to the chaotic dynamics in their nonlinear oscillators. The dynamics of the last two residues are also chaotic for the same reason. Interesting synchronized domains occur in the middle for partially folded residues. (e) The ${\mathrm{C}}_{\alpha }$ atoms of more disordered Conformation 28. (f) The more chaotic dynamics of Conformation 28 showing a higher degree of randomness. Unfolded residues are in their chaotic motions. Compared to the dynamical behavior of Conformation 14, there are fewer synchronized domains and an average synchronized domain involves fewer oscillators. (g) The ${\mathrm{C}}_{\alpha }$ atoms of completely unfolded Conformation 41. (h) The completely chaotic dynamics of Conformation 41 showing 336-dimensional chaotic motions.