Figure 1. Frequencies of C4B*Q0 carriers (with zero or one C4B gene in the diploid genome) in healthy German individuals of different age-groups.
p_case_contr: p value for the comparison of C4B*Q0 carrier frequencies between long-lived cases and younger controls (Fisher's exact test; primary endpoint). p_contr_trend: p value for trend test of C4B*Q0 carrier frequencies in the three control subgroups (Armitage trend test; secondary endpoint). p_case: p value for the comparison of C4B*Q0 frequencies in the two case subgroups (Fisher's exact test; secondary endpoint). p_trend: p value for trend test of C4B*Q0 frequencies in all five age groups (Armitage trend test; secondary endpoint).