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. 2014 Jan 22;9(1):e86147. doi: 10.1371/journal.pone.0086147

Figure 1. Wound healing progress in WHM.

Figure 1

Effect of TE and betulin on reepithelialization in the porcine ex-vivo WHM. (A) Reepithelialization in WHM treated with 10% TE in sunflower oil (oleogel) compared to sunflower oil alone, sunflower oil with ethylcellulose and untreated control 48 h after wounding. (B) Reepithelialization in WHM treated with 10 µg/ml TE and betulin in the concentration as it occurs in 10 µg/ml TE in PBS compared to PBS 48 h after wounding. Reepithelialization of the various models was normalized to untreated control (A) or PBS (B), respectively. Mean ± SEM. (C) Effect of TE and betulin in PBS on barrier regeneration in WHM normalized to barrier regeneration in WHM treated with PBS alone. WHM were treated 72 h after wounding for 24 h. Mean ± SEM. A: n = 7; B: n = 5–7; C: n = 4–5. *p<0.05 and ***p<0.001.