Table 1. NK cell activation ADCC response to HIV is not HLA-restricted.
NK cell donor | HLA A | HLA B | HLA C | HLA DRB1 | HLA DQA1 | HLA DQB1 | ADCC response* |
---|---|---|---|---|---|---|---|
S1 | 03:01;26:01 | 27:05;27:05 | 01:02;02:02 | 1,9 | 1,3 | 3,5 | 18.3 |
C1 | 02:01;68:01 | 51:01;60:01 | 03:04;15:04 | 13,14 | 1,1 | 5,6 | 19.8 |
C2 | 11:01;24:02 | 48:03;62:01 | 03:03;08:01 | 11,14 | 1,5 | 3,5 | 18.1 |
C3 | 03:01;33:03 | 44:03;52:01 | 07:01;12:02 | 4,7 | 2,3 | 2,3 | 3.1 |
C4 | 02:01;03:01 | 35:03;51:01 | 04:01;16:02 | 4,15 | 1,3 | 3,6 | 8.8 |
C5 | 02:01;23:01 | 44:03;57:01 | 04:01;06:02 | 7,12 | 2,5 | 2,2 | 7.1 |
C6 | 01:01;02:01 | 08:01;39:01 | 07:01;12:03 | 1,3 | 1,5 | 2,5 | 8.2 |
C7 | 03:01;29:01 | 07:01;44:01 | 07:01;16:02 | 7,15 | 1,2 | 2,6 | 4.8 |
C8 | 11:01;24:07 | 38:02;75:21 | 04:03;07:02 | 15,15 | 1,2 | 5,6 | 15 |
C9 | 29:01;30:02 | 18:01;38:01 | 05:01;12:03 | 3,14 | 1,5 | 2,5 | 10.9 |
*% NK cells expressing IFNγ