. 2013 Jan 31;9(5):993–1001. doi: 10.4161/hv.23800

Table 1. Calculated EC₅₀ (in nM) of HDAC inhibitors.

	Belinostat	Givinostat	Vorinostat	Panobinostat	Valproate
U1 cells
EC₅₀ (CI), nM	274.7 (211.2–357.3)	254.3 (192.2–336.0)	1197 (818.7–1750)	12.78 (11.22–14.56)	1531000 (219049–1.070e+007)
ACH2 cells
EC₅₀ (CI), nM	255.1 (Very wide)	360 (218.6–592.9)	885.3 (626.4–1251)	15.95 (7.581–33.58)	993029 (Very wide)

The half maximal effective concentration (EC₅₀) for each HDAC inhibitor in U1 and ACH2 cells normalized to PMA-induced viral production. CI, confidence interval.

Table 1. Calculated EC50 (in nM) of HDAC inhibitors.

Table 1. Calculated EC₅₀ (in nM) of HDAC inhibitors.