Figure 2. Chemotherapy of both morphological types of XPA1 cells in vivo. (A and B) Images of tumors at termination. (C and D) Bar graphs of tumor weight. 5-FU and A1-R significantly reduced the tumor weight of round non-stem XPA1 cells (5-FU; P = 0.028, A1-R; P = 0.011) (B and D), whereas only A1-R significantly reduced the tumor weight of spindle-shaped stem-like XPA1 cells compared with control (P = 0.012) (A and C). *P < 0.05 (vs. control group). BF, bright field.