Figure 5. Combination chemotherapy efficacy for stem-like XPA1 cells in vivo. (A) Images of tumors at termination. (B) Bar graphs of tumor weight. Every group significantly reduced tumor weight compared with control (5-FU, P = 0.039; A1-R, P < 0.001; 5-FU + A1-R, P < 0.001). Combination therapy (5-FU + A1-R) significantly reduced tumor weight compared with 5-FU (P = 0.004), even though the dosage of each drug was reduced compared with monotherapy (B) BF, brightfield.