Table 1. Genetic interactions between the Dma proteins and other factors involved in cytokinesis.
Genotype | Phenotype at 25 °C on YEPD | Phenotype at 25 °C on YEPRG |
---|---|---|
dma1Δ dma2Δ chs2Δ | healthy | ND |
dma1Δ dma2Δ iqg1-1 | healthy | ND |
dma1Δ dma2Δ cyk3Δ | sick/slow growth | ND |
dma1Δ dma2Δ hof1Δ | healthy | ND |
GAL1-DMA2 chs2Δ | healthy | healthy |
GAL1-DMA2 iqg1–1 | healthy | sick/slow growth |
GAL1-DMA2 cyk3Δ | healthy | healthy |
GAL1-DMA2 hof1Δ | healthy | lethal |
GAL1-DMA1 hof1Δ | healthy | lethal |
Strains carrying DMA1 and DMA2 deletions or expressing GAL1-DMA2 or GAL1-DMA1 were crossed with the chs2Δ, iqg1-1, cyk3Δ, and hof1Δ mutants. The resulting diploids were induced to sporulate and meiotic segregants were assayed for their ability to grow on rich medium containing glucose (YEPD) or galactose (YEPRG) at 25 °C. Only the phenotypes of meiotic segregants with the indicated genotypes are shown, the meiotic segregants with all the other possible genotypes all showed healthy phenotypes. ND, not determined.