Figure 3. Burkitt lymphoma cell lines are variably sensitive to AKIs. Cell lines were treated with the noted concentrations of AKIs for 48 h, after which cells were stained with annexin V antibody and propidium iodide and the percent annexin-positive cells were determined. Results from at least 3 experiments are shown. P < 0.0001 for all AKI treatments compared with control. VX, VX-680; MLN, MLN8237; ZM, ZM447439.