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The nature of the lh-2 mutation. A, Agarose (2% [w/v])/Tris-acetate EDTA (TAE) electophoresis gel of PCR products with the same primers from wild-type, lh-1, and lh-2 cDNA. B, Schematic diagram of lh-2 mutation. C, Comparison of genomic and cDNA sequence from wild type and lh-2 to illustrate the lh-2 genetic lesion.
