Table 1. Characteristics of studies included in meta-analysis.
Study | publication year | Country | Ethnicity | FTO SNP | Sample size | Mean age(years) | Mean BMI(kg/m2) | OR | 95%CI | P HWE a | |||
cases | controls | cases | controls | cases | controls | ||||||||
Yan et al. [12] | 2009 | China | East Asian | rs9939609 | 215 | 227 | 21.7 | 27.5 | 28.0 | 20.8 | 1.39 | 0.76–2.52 | 0.36 |
Hatziagelaki et al.[18] | 2012 | Germany | Caucasian | rs8050136 | 62 | 105 | 26.0 | 27.0 | 27.3 | 26.6 | 1.24 | 0.58–2.64 | 0.49 |
Kim et al. [19] | 2012 | Korea | East Asian | rs1421085 | 377 | 386 | 28.5 | 28.5 | 22.2 | 20.1 | 1.13 | 0.47–2.68 | 0.46 |
Saxena et al.[5] | 2012 | USA | Caucasian | rs9939609 | 525 | 472 | 28.4 | 28.9 | 30.8 | 23.5 | 1.03 | 0.83–1.28 | 0.69 |
Li et al. [16] | 2013 | China | East Asian | rs9939609 | 3599 | 3082 | 28.4 | 31.3 | 24.8 | 22.7 | 1.44 | 1.30–1.60 | 0.74 |
OR = odds ratio, CI = confidence interval, SNP = single nucleotide polymorphism.
P value for Hardy–Weinberg equilibrium test (HWE) in controls.