Table 3. Age at onset and mean disease duration by disease subtype in fatal cases.
| Age at onset (years) |
Alla (months) (n = 855) |
Subtypeb | ||||
| sCJD (months) (n = 674) |
fCJD (months) (n = 93) |
dCJD (months) (n = 63) |
GSS (months) (n = 20) |
FFI (months) (n = 3) |
||
| –39 | 43.2 (n = 16) | 26.8c (n = 4) | 143.4c (n = 1) | 30.5c (n = 9) | 83.4 (n = 2) | — |
| 40–59 | 23.1 (n = 184) | 20.7c (n = 129) | 16.5c (n = 20) | 21.9c (n = 18) | 65.3 (n = 12) | 10.6 (n = 3) |
| 60–79 | 15.9 (n = 573) | 15.2c (n = 473) | 18.5c (n = 59) | 15.7c (n = 35) | 47.1 (n = 6) | — |
| 80+ | 10.9 (n = 82) | 9.9c (n = 68) | 15.9c (n = 13) | 11.6c (n = 1) | — | — |
aVariant CJD and undetermined CJD were included.
bThe legend for abbreviations of subtype is in Table 1.
cDifferences in mean disease duration among 3 types of CJD (sCJD, fCJD, and dCJD) and between age groups at onset were tested by using 2-way analysis of variance. The probabilities were 0.007 for subtype and 0.071 for age group.