Fig. 1.

Scatterplot of 1,000 bootstrap replicates showing the incremental cost and incremental effectiveness of the paricalcitol regimen compared with the cinacalcet-based regimen, where effectiveness is the proportion of subjects reaching an intact parathyroid hormone (iPTH) level of 150–300 pg/mL (the primary endpoint). All simulation results fell within two quadrants of the cost-effectiveness plane: (1) the lower right quadrant, where the paricalcitol regimen is both less expensive and more effective than cinacalcet (i.e. dominant), containing 99.1 % of the replicates; and (2) the lower left quadrant, where the paricalcitol regimen is less expensive but less effective, containing 0.9 % of the replicates