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Results of gene–gene interactions analyzed by multifactor dimensionality reduction method
| Polymorphisms | Testing balanced accuracy | Cross validation consistency (%) | p valuea |
|---|---|---|---|
| CTNNB1_rs4533622, APC_rs11954856 | 0.5418 | 60 | 0.356 |
| CTNNB1_rs4533622, APC_rs351771, AXIN2_rs4074947 | 0.5041 | 50 | 0.828 |
| CTNNB1_rs4533622, APC_rs11954856, AXIN2_rs7224837, AXIN2_rs2240308 | 0.5719 | 100 | 0.068 |
aSignificance of accuracy (empirical p value based on 1,000 permutations)
