Table 1. Age-adjusted means (SE) for lipid parameters, according to selected participant characteristics and risk factors for breast cancer.
| Characteristic | No. | Total cholesterol (mmol/L) |
HDL cholesterol (mmol/L) |
LDL cholesterol (mmol/L) |
Triglyceride (mmol/L) |
|||||
| Mean (SE) | Ptrenda | Mean (SE) | Ptrenda | Mean (SE) | Ptrenda | Mean (SE) | Ptrenda | |||
| Age (years) | <45 | 353 | 4.59 (0.04) | <0.01 | 1.39 (0.02) | <0.01 | 2.63 (0.04) | <0.01 | 0.92 (0.04) | <0.01 |
| 45–59 | 223 | 5.05 (0.06) | 1.32 (0.02) | 3.01 (0.05) | 1.25 (0.05) | |||||
| ≥60 | 135 | 5.34 (0.07) | 1.32 (0.03) | 3.23 (0.06) | 1.57 (0.06) | |||||
| Percent dense area (%) | <14.71 | 177 | 4.93 (0.08) | 0.05 | 1.26 (0.03) | <0.01 | 2.98 (0.07) | <0.01 | 1.31 (0.07) | <0.01 |
| 14.71–33.77 | 179 | 4.99 (0.06) | 1.36 (0.02) | 2.95 (0.05) | 1.21 (0.05) | |||||
| 33.78–59.89 | 177 | 4.80 (0.06) | 1.37 (0.02) | 2.79 (0.06) | 1.11 (0.06) | |||||
| ≥50.90 | 178 | 4.77 (0.07) | 1.44 (0.03) | 2.73 (0.06) | 0.97 (0.06) | |||||
| Dense area (cm2) | <14.56 | 177 | 4.89 (0.07) | 0.98 | 1.30 (0.03) | 0.31 | 2.90 (0.06) | 0.94 | 1.27 (0.07) | 0.32 |
| 14.56–32.51 | 178 | 4.83 (0.06) | 1.38 (0.02) | 2.81 (0.05) | 1.09 (0.05) | |||||
| 32.52–48.01 | 178 | 4.92 (0.06) | 1.37 (0.02) | 2.88 (0.06) | 1.12 (0.06) | |||||
| ≥48.02 | 178 | 4.86 (0.07) | 1.37 (0.02) | 2.86 (0.06) | 1.12 (0.06) | |||||
| Body mass index (kg/m2) | <18.5 | 15 | 4.98 (0.21) | <0.01 | 1.55 (0.08) | <0.01 | 2.83 (0.18) | <0.01 | 0.89 (0.18) | <0.01 |
| 18.5–22.9 | 318 | 4.77 (0.05) | 1.41 (0.02) | 2.75 (0.04) | 0.99 (0.04) | |||||
| 23.0–24.9 | 154 | 4.88 (0.07) | 1.35 (0.02) | 2.90 (0.06) | 1.11 (0.06) | |||||
| ≥25 | 202 | 5.02 (0.06) | 1.25 (0.02) | 3.02 (0.05) | 1.44 (0.05) | |||||
| Smoking status | Never | 636 | 4.87 (0.03) | 0.55 | 1.34 (0.01) | <0.01 | 2.87 (0.03) | 0.22 | 1.15 (0.03) | 0.69 |
| Ever | 69 | 4.81 (0.10) | 1.46 (0.04) | 2.76 (0.09) | 1.11 (0.09) | |||||
| Alcohol drinking | No | 379 | 4.84 (0.04) | 0.31 | 1.32 (0.02) | <0.01 | 2.87 (0.04) | 0.77 | 1.12 (0.04) | 0.41 |
| Yes | 326 | 4.91 (0.05) | 1.40 (0.02) | 2.86 (0.04) | 1.17 (0.04) | |||||
| Physical exercise | No | 462 | 4.86 (0.04) | 0.59 | 1.34 (0.01) | 0.38 | 2.86 (0.03) | 0.99 | 1.16 (0.03) | 0.59 |
| Yes | 236 | 4.90 (0.05) | 1.37 (0.02) | 2.86 (0.05) | 1.13 (0.05) | |||||
| Duration of education (years) | <12 | 222 | 4.96 (0.07) | 0.05 | 1.30 (0.03) | 0.02 | 2.94 (0.06) | 0.10 | 1.25 (0.06) | 0.03 |
| 12–15 | 332 | 4.87 (0.05) | 1.37 (0.02) | 2.85 (0.04) | 1.13 (0.04) | |||||
| ≥16 | 155 | 4.75 (0.07) | 1.40 (0.03) | 2.78 (0.06) | 1.04 (0.06) | |||||
| Age at menarche (years) | <12 | 81 | 4.74 (0.09) | 0.13 | 1.37 (0.04) | 0.28 | 2.70 (0.08) | 0.19 | 1.29 (0.08) | 0.76 |
| 13 | 108 | 4.87 (0.08) | 1.38 (0.03) | 2.91 (0.07) | 1.06 (0.07) | |||||
| 14 | 160 | 4.83 (0.07) | 1.36 (0.03) | 2.85 (0.06) | 1.10 (0.06) | |||||
| 15 | 141 | 4.84 (0.07) | 1.34 (0.03) | 2.81 (0.06) | 1.22 (0.06) | |||||
| ≥16 | 196 | 4.96 (0.06) | 1.34 (0.03) | 2.92 (0.06) | 1.13 (0.06) | |||||
| Age at first childbirth (years) | <25 | 194 | 4.97 (0.06) | 0.19 | 1.33 (0.02) | 0.25 | 2.90 (0.05) | 0.55 | 1.29 (0.06) | 0.05 |
| 25–29 | 358 | 4.85 (0.04) | 1.35 (0.02) | 2.85 (0.04) | 1.11 (0.04) | |||||
| ≥30 | 90 | 4.86 (0.09) | 1.38 (0.03) | 2.86 (0.08) | 1.15 (0.08) | |||||
| No. live children | None | 59 | 4.98 (0.12) | 0.52 | 1.44 (0.05) | <0.01 | 2.95 (0.10) | 0.60 | 1.13 (0.11) | 0.08 |
| 1–2 | 395 | 4.85 (0.05) | 1.39 (0.02) | 2.83 (0.04) | 1.09 (0.04) | |||||
| 3–4 | 164 | 4.94 (0.07) | 1.29 (0.03) | 2.94 (0.06) | 1.22 (0.07) | |||||
| ≥5 | 73 | 4.75 (0.12) | 1.25 (0.05) | 2.76 (0.11) | 1.38 (0.11) | |||||
| Duration of breast feeding | Never | 59 | 5.01 (0.12) | 0.19 | 1.42 (0.04) | <0.01 | 2.99 (0.10) | 0.38 | 1.19 (0.09) | 0.32 |
| (months) | <6 | 135 | 4.91 (0.07) | 1.43 (0.03) | 2.86 (0.06) | 1.08 (0.06) | ||||
| 6–11 | 99 | 4.82 (0.08) | 1.37 (0.03) | 2.80 (0.07) | 1.09 (0.07) | |||||
| 12–23 | 145 | 4.87 (0.07) | 1.33 (0.03) | 2.88 (0.06) | 1.17 (0.06) | |||||
| ≥24 | 162 | 4.79 (0.08) | 1.28 (0.03) | 2.80 (0.06) | 1.20 (0.06) | |||||
| Use of oral contraceptive pill | Never | 579 | 4.87 (0.03) | 0.97 | 1.35 (0.01) | 0.23 | 2.85 (0.03) | 0.76 | 1.16 (0.03) | 0.32 |
| Ever | 110 | 4.87 (0.08) | 1.39 (0.03) | 2.88 (0.07) | 1.09 (0.07) | |||||
| Hormone replacement therapy | Never | 186 | 5.26 (0.07) | 0.61 | 1.31 (0.02) | 0.66 | 3.19 (0.06) | 0.47 | 1.48 (0.07) | 0.75 |
| (among postmenopausal women) | Ever | 61 | 5.19 (0.12) | 1.33 (0.04) | 3.10 (0.11) | 1.43 (0.12) | ||||
| Menopause | No | 456 | 4.87 (0.05) | 0.93 | 1.36 (0.02) | 0.61 | 2.85 (0.04) | 0.64 | 1.10 (0.04) | 0.12 |
| Yes | 255 | 4.88 (0.08) | 1.34 (0.03) | 2.89 (0.07) | 1.25 (0.07) | |||||
HDL, high-density lipoprotein; LDL, low-density lipoprotein; SE, standard error.
aAssessed by age-adjusted linear regression analysis.