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. 2014 Jan 23;4:394. doi: 10.3389/fphys.2013.00394

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Copyright © 2014 Nielsen, Hvid, Kelly, Lindegaard, Dethlefsen, Winding, Mathur, Scheele, Pedersen and Laye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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myomiR expression in testosterone treated human muscle cells. myomiR expression in differentiated human primary myocytes in response to 100 nM testosterone (n = 4), and 5α-DHT (n = 4). Control cultures (n = 4) were added DMSO in same concentrations as testosterone and 5α-DHT stimulated myocytes. miR-133a/b was upregulated in response to 5α-DHT treatment and mirR-206 expression was downregulated in response to to testosterone treatment (^*P < 0.05) (A). Whereas the expression of Myf-5 was upregulated in response to 5α-DHT and testosterone (^*P < 0.05) no regulation of Myod, Myog or AR was detected (B). Data are mean ± SEM.