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L-plastin knock-down reduces cancer cell migration in vitro. SDF1α (350 ng/ml) mediated migration towards the integrin ligand collagen I of PC3M nt shRNA and PC3M LPL shRNA cells was analyzed as described in material and methods. Cells were incubated for 18 hours for migration assays. Results were analyzed using student’s t-test, data represent means ± SEM (n ≥ 3; * = p < 0.05).
