Table 4.
Association of GATA4 haplotypes with metabolic disease risk traits
| |
Controls |
Cases |
||||
|---|---|---|---|---|---|---|
| All | Male | Female | All | Male | Female | |
| Gender |
2,004 |
1,074 (53.6) |
930 (46.4) |
2,274 |
1,736 (76.3) |
538 (23.7) |
| Age |
50.2 ± 0.5 |
50.81 ± 0.5 |
49.66 ± 0.5 |
60.8 ±0.4 |
59.7 ± 0.3 |
61.8 ± 0.5 |
| BMI |
29.4 ±0.2 |
28.01 ± 0.2 |
30.69 ± 0.2 |
29.7 ± 0.2 |
28.3 ± 0.1 |
31.1 ± 0.3 |
| MI |
1,388 |
684 (0.49) |
704 (0.51) |
2,890 |
2,126 (0.74) |
764 (0.26) |
| T2DM |
1,900 |
1,220 (0.64) |
680 (0.36) |
2,378 |
1,590 (0.67) |
788 (0.33) |
| HTN |
966 |
650(0.67) |
314 (0.33) |
3,312 |
2,158 (0.65) |
1,154 (0.35) |
| lHDLC |
2,209 |
1,262 (0.57) |
947 (0.43) |
1,776 |
1,371 (0.77) |
405 (0.23) |
| hLDL |
3,404 |
2,267 (0.67) |
1,137 (0.33) |
575 |
364 (0.63) |
211 (0.37) |
| hTG |
2,896 |
1,859 (0.64) |
1,037 (0.36) |
1,088 |
773 (0.71) |
315 (0.29) |
| hChol |
2,487 |
1,639 (0.66) |
848 (0.34) |
1,590 |
1,051 (0.66) |
539 (0.34) |
| CHD |
4,128 |
2,741 (0.66) |
1,387 (0.34) |
150 |
69 (0.46) |
81 (0.54) |
| FH |
3,421 |
2,255 (0.66) |
1,166 (0.34) |
857 |
555 (0.65) |
302 (0.35) |
| OBS |
2,362 |
1,729 (0.73) |
633 (0.27) |
1,631 |
895 (0.55) |
736 (0.45) |
| Smokers |
2,575 |
1,223 (0.47) |
1,352 (0.53) |
1,619 |
1,547 (0.96) |
72 (0.04) |
| VD |
|
|
|
|
|
|
| One |
0 |
0 |
0 |
847 |
614 (0.72) |
233 (0.28) |
| Two |
0 |
0 |
0 |
456 |
355 (0.78) |
101 (0.22) |
| More than two | 0 | 0 | 0 | 971 | 767 (0.79) | 204 (0.21) |
The numbers in brackets give the percentages of the total (all) values of the group. BMI, body mass index; CHD, congenital heart disease; FH, family history of CAD; MI, myocardial infarction; lHDLC, low high-density lipoprotein-cholesterol level; hTG, hypertriglyceridaemia; hChol, hypercholesterolaemia; HTN, hypertension; T2DM, type 2 diabetes mellitus; VD, number of diseased vessels.