Table 1. EIF5A2 staining and clinicopathological characteristics of 382 melanomas.
|
EIF5A2 staining |
|
||||
|---|---|---|---|---|---|
| Variables | Positive number (%) | Negative number (%) | Total | χ2- value | P-value |
|
All melanoma (n=382) | |||||
|
Age, years | |||||
| ⩽60 | 161 (81.3) | 37 (18.7) | 198 | 0.552 | 0.458 |
| >60 |
144 (78.3) |
40 (21.7) |
184 |
|
|
|
Sex | |||||
| Male | 191 (83.4) | 38 (16.6) | 229 | 0.834 | 0.361 |
| Female |
122 (79.7) |
31 (20.3) |
153 |
|
|
|
AJCC stage | |||||
| I | 88 (69.3) | 39 (30.7) | 127 | 4.046 | 0.044a |
| II | 103 (89.6) | 12 (10.4) | 115 | ||
| III | 48 (88.9) | 6 (11.1) | 54 | ||
| IV |
74 (86.0) |
12 (14.0) |
86 |
|
|
|
Primary melanoma (n=242) | |||||
|
Age, years | |||||
| ⩽61 | 95 (77.2) | 28 (22.8) | 123 | 0.429 | 0.512 |
| >61 |
96 (80.7) |
23 (19.3) |
119 |
|
|
|
Sex | |||||
| Male | 105 (78.9) | 28 (21.1) | 133 | 0.000 | 1.000 |
| Female |
86 (78.9) |
23 (21.1) |
109 |
|
|
|
Tumour thickness (mm) | |||||
| ⩽2 | 94 (70.1) | 40 (29.9) | 134 | 13.90 | <0.001 |
| >2 |
97 (89.8) |
11 (10.2) |
108 |
|
|
|
Ulceration | |||||
| Absent | 146 (75.3) | 48 (24.7) | 194 | 7.911 | 0.005 |
| Present |
45 (93.7) |
3 (6.3) |
48 |
|
|
|
Subtype | |||||
| Lentigo maligna | 26 (70.3) | 11 (29.7) | 37 | 2.828 | 0.419 |
| Superficial spreading | 69 (77.5) | 20 (22.5) | 89 | ||
| Nodular | 35 (85.4) | 6 (14.6) | 41 | ||
| Unspecified |
61 (81.3) |
14 (18.7) |
75 |
|
|
|
Siteb | |||||
| Sun protected | 150 (79.8) | 38 (20.2) | 188 | 0.376 | 0.540 |
| Sun exposed |
41 (76.0) |
13 (24.0) |
54 |
|
|
|
Metastatic melanoma (n=140) | |||||
|
Age, years | |||||
| ⩽59 | 63 (86.3) | 10 (13.7) | 73 | 0.096 | 0.757 |
| >59 |
59 (88.1) |
8 (11.9) |
67 |
|
|
|
Sex | |||||
| Male | 86 (89.6) | 10 (10.4) | 96 | 1.624 | 0.203 |
| Female | 36 (81.8) | 8 (18.2) | 44 | ||
Abbreviation: AJCC=American Joint Committee on Cancer.
a
Comparison between AJCC stage I–II and III–IV, χ2-test.
b
Sun-protected sites: trunk, arm, leg and feet; sun-exposed sites: head and neck.