Table 3. Univariate and multivariate analysis of individual variables for disease-free survival.
| Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|
|
Risk factors |
Abbreviation |
HR |
95% CI |
P-value |
HR |
95% CI |
P-value |
| FIGO stage |
ST2 |
1.900 |
1.229–2.937 |
0.004 |
1.482 |
0.940–2.339 |
0.091 |
| Adeno or adenosquamous |
ADE |
1.469 |
1.011–2.134 |
0.043 |
1.743 |
1.194–2.545 |
0.004 |
| Tumour size⩾2 cm |
2CM |
4.883 |
1.997–11.938 |
0.001 |
4.588 |
1.871–11.248 |
0.001 |
| Tumour size⩾3 cm |
3CM |
2.756 |
1.815–4.184 |
0.000 |
2.512 |
1.645–3.835 |
0.000 |
| Tumour size⩾4 cm |
4CM |
1.833 |
1.289–2.606 |
0.001 |
1.481 |
1.024–2.142 |
0.037 |
| Tumour size ⩾5 cm |
5CM |
2.038 |
1.319–3.151 |
0.001 |
1.537 |
0.978–2.415 |
0.062 |
| Stromal invasion ⩾middle 1/3 of cervical wall |
MID |
1.845 |
1.246–2.734 |
0.002 |
1.303 |
0.861–1.973 |
0.211 |
| Stromal invasion ⩾outer 1/3 of cervical wall |
OUT |
2.020 |
1.435–2.843 |
0.000 |
1.566 |
1.091–2.247 |
0.015 |
| LVSI positive |
LVSI |
2.015 |
1.426–2.847 |
0.000 |
1.845 |
1.265–2.690 |
0.001 |
| Adjuvant treatment | ADJ | 1.957 | 1.355–2.827 | 0.000 | 1.372 | 0.910–2.069 | 0.131 |
Abbreviations: CI=confidence interval; FIGO=International Federation of Gynecology and Obstetrics; HR=hazard ratio; LVSI=lymphovascular space involvement.