Table 1. Baseline patients characteristics.
| |
Arm A (N=45) |
Arm B (N=44) |
||
|---|---|---|---|---|
| Characteristics | N | % | N | % |
|
Age (years) | ||||
| Median, range | 65 | 33–80 | 62 | 29–78 |
| <65 | 22 | 49 | 25 | 59 |
| ⩾65 |
23 |
51 |
19 |
41 |
|
Gender | ||||
| Male | 29 | 64 | 32 | 73 |
| Female |
16 |
36 |
12 |
27 |
|
ECOG PS | ||||
| 0 | 23 | 51 | 22 | 50 |
| 1 | 18 | 40 | 18 | 41 |
| 2 |
4 |
9 |
4 |
9 |
|
Prior gastrectomy | ||||
| Yes |
20 |
44 |
21 |
48 |
|
Adjuvant chemotherapy | ||||
| Yes |
11 |
24 |
16 |
36 |
|
Previous lines of chemotherapy | ||||
| 1 | 25 | 56 | 24 | 55 |
| ⩾2 |
20 |
44 |
20 |
45 |
|
Prior chemotherapy | ||||
| Fluoropyrimidine | 45 | 100 | 43 | 98 |
| Platinum agent | 35 | 78 | 34 | 77 |
| Irinotecan | 17 | 38 | 18 | 41 |
| Other |
7 |
16 |
8 |
18 |
|
Measurable lesions | ||||
| Present |
35 |
78 |
33 |
75 |
|
Metastatic sites | ||||
| Lymph node | 30 | 67 | 28 | 64 |
| Peritoneum | 19 | 42 | 21 | 48 |
| Liver | 16 | 36 | 13 | 30 |
| Lung | 4 | 9 | 4 | 9 |
| Bone |
3 |
7 |
4 |
9 |
|
No. of metastatic sites | ||||
| 1 | 18 | 40 | 15 | 34 |
| ⩾2 | 27 | 60 | 29 | 66 |
Abbreviation: ECOG PS=Eastern Cooperative Oncology Group performance status.