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. Author manuscript; available in PMC: 2014 Jan 23.
Published in final edited form as: Nat Med. 2013 Apr 21;19(5):595–602. doi: 10.1038/nm.3111

Figure 2. Peli1 deficiency in radioresistant cells inhibits immune cell recruitment into the CNS and ameliorates EAE pathogenesis.

Figure 2

(a) EAE induction of wild-type and Peli1-KO mice adoptively transferred with GFP+ wild-type BM cells. (b–e) Flow cytometry analysis of total CNS-infiltrating cells (GFP+, b,c) and CNS-infiltrating CD4 T cells (GFP+CD4+, d,e) of the MOG35-55-immunized wild-type and Peli1-KO GFP-chimeric mice described in a, showing a representative plot (b,d) and a summary graph (c,e). (f) Flow cytometry analysis of GFP+CD4+ cell number in the spleen of MOG35-55-immunized wild-type and Peli1-KO GFP-chimeric mice. (g) QPCR analysis of the indicated genes. *P<0.05 and **P<0.01.