Table V.
Baseline covariates for the 311 subjects in the PBC data. Numbers in parenthesis for continuous variables are the standard deviations.
| Placebo (n=157) | D-penicillamine (n=154) | |
|---|---|---|
| Male | 20 (12.7%) | 15 (9.7%) |
| Age (year) | 51.4 (11.0) | 48.6 (10.0) |
| Presence of ascites | 143 (91.1%) | 144 (93.5%) |
| Presence of hepatomegaly | 85 (54.1%) | 67 (43.5%) |
| Presence of spiders | 112 (71.3%) | 109 (70.1%) |
| Presence of edema | ||
| 0 | 131 (83.4%) | 131 (85.1%) |
| 1 | 16 (10.2%) | 13 (8.4%) |
| 2 | 10 (6.4%) | 10 (6.5%) |
| Serum bilirubin (mg/dl) | 2.88 (3.64) | 3.65 (5.28) |
| Albumin (gm/dl) | 3.52 (0.44) | 3.52 (0.40) |
| Alkaline phosphatase (U/liter) | 156 (87) | 144 (83) |
| SGOT (U/ml) | 91.3 (53.7) | 90.7 (54.6) |
| Prothrombin time (seconds) | 18.2 (16.1) | 21.4 (16.5) |
| Histologic stage | ||
| 1 | 12 (7.6%) | 4 (2.6%) |
| 2 | 35 (22.3%) | 32 (20.8%) |
| 3 | 56 (35.7%) | 64 (41.6%) |
| 4 | 54 (34.4%) | 54 (35.1%) |