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At the fibre level, some transverse and longitudinal moduli were estimated from finite-element simulation of the mechanical response of a representative unit cell. The unit cell shown with approximately 20 000 reduced integration tetrahedral elements was adequate for convergence of simulations of unmineralized collagen fibres. Significantly finer meshes discretized to allow sheaths of mineral were required for simulations of partially mineralized fibres. (Online version in colour.)
