Figure 3.

Modules of the computational model. (a) Cell motility by a copy of the membrane outwards (1) and inwards (2). (b) Cell surface polarization, resulting in cytoplasm (blue) surrounded by a basolateral membrane (grey) and an apical membrane (orange). (c) Vesicles (red) can be created by pinocytosis (3), move in the cell by a biased random walk (4), fuse into vacuoles (yellow) (5) and be secreted (6) into luminal fluid (light blue). (d) The apical membranes of different cells repulse each other (7) owing to the negative charges on the extracellular domains of the CD34-sialomucins herein.